Crystal structure of bisphosphorylated IGF1-R Kinase domain (2P) in complex with a bis-azaindole inhibitor
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Crystal structure of bisphosphorylated IGF1-R Kinase domain (2P) in complex with a bis-azaindole inhibitor Descriptor: 3-(4-chloro-1H-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dimethoxy-1-methyl-1H-pyrrolo[3,2-b]pyridine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Insulin-like growth factor 1 receptor, ... Authors: Maignan, S, Marquette, J.P, Guilloteau, J.P. Deposit date: 2010-02-22 Release date: 2010-07-21 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (3 Å) Cite: Design of Potent IGF1-R Inhibitors Related to Bis-azaindoles Chem.Biol.Drug Des., 76, 2010
双磷酸化胰岛素样生长因子1受体（Insulin-like growth factor 1 receptor, IGF1-R）激酶结构域（2P）与双氮吲哚类抑制剂的共晶结构。相关描述：3-(4-氯-1H-吡咯并[2,3-b]吡啶-2-基)-5,6-二甲氧基-1-甲基-1H-吡咯并[3,2-b]吡啶、4-(2-羟乙基)-1-哌嗪乙磺酸、胰岛素样生长因子1受体……。作者：Maignan S、Marquette J.P、Guilloteau J.P。提交日期：2010-02-22，发布日期：2010-07-21，最后修改日期：2023-11-01。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率3 Å。引用：《Design of Potent IGF1-R Inhibitors Related to Bis-azaindoles》，发表于Chem.Biol.Drug Des. 2010年第76卷
创建时间：
2010-02-22
