SNPs showing interaction with sex and vascular risk factors for presence or number of carotid plaque with a nominal p≤0.01.
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*Pvrf, Psnp, Pinteraction and beta were, respectively, p-value for risk factor main effect, p-value for SNP main effect, p-value and regression coefficient for their interactive effect, based on Logistic (plaque presence) and Poisson (plaque count) regression models after adjusting for age, sex, smoking, hypertension, diabetes and waist-to-hip ratio as well as genomic control variables (PCAs) if applicable.
Pvrf、Psnp、Pinteraction与beta分别对应风险因素主效应p值、单核苷酸多态性(Single Nucleotide Polymorphism, SNP)主效应p值、二者交互效应的p值及回归系数。上述统计量均基于Logistic回归(用于分析斑块存在情况)与Poisson回归(用于分析斑块数量)模型构建,且已校正年龄、性别、吸烟史、高血压、糖尿病、腰臀比,以及若适用的基因组对照变量(主成分分析,PCAs)。
创建时间:
2015-12-02



