Structural basis of thrombin mediated factor V activation: essential role of the hirudin-like sequence Glu666-Glu672 for processing at the heavy chain-B domain junction
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Structural basis of thrombin mediated factor V activation: essential role of the hirudin-like sequence Glu666-Glu672 for processing at the heavy chain-B domain junction Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... Authors: Corral-Rodriguez, M.A, Bock, P.E, Hernandez-Carvajal, E, Gutierrez-Gallego, R, Fuentes-Prior, P. Deposit date: 2010-10-11 Release date: 2011-06-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction. Blood, 117, 2011
凝血酶介导的凝血因子V(factor V)激活的结构基础:水蛭素样序列(hirudin-like sequence)Glu666-Glu672在重链-B结构域连接处切割中的关键作用
描述物:(4S)-2-甲基-2,4-戊二醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、氯离子……
作者:Corral-Rodríguez, M.A.、Bock, P.E.、Hernández-Carvajal, E.、Gutiérrez-Gallego, R.、Fuentes-Prior, P.
提交日期:2010年10月11日
发布日期:2011年6月15日
最后修改日期:2024年10月30日
研究方法:X射线衍射(分辨率1.7 Å)
引用文献:凝血酶介导的凝血因子V(factor V)激活的结构基础:Glu666-Glu672序列在重链-B结构域连接处的切割至关重要。《Blood》,117卷,2011年
创建时间:
2010-10-11



