Sequences at the integration sites aligned to the L1 endonuclease cleavage consensus site.

AA-TTTT L1 endonuclease cleavage consensus site.*This integration site cannot be unequivocally determined due to an associated 71-bp deletion and the lack of a TSD. The given integration site assumes either a model where the second nick occurred downstream instead of upstream to the first nick that affected the NF1 sense strand or a model where the reverse transcribed Alu cDNA strand (termed minus strand) invaded a double-strand break 71 bp downstream of the given integration site. Integration sites indicated with the same symbole §, # or ‡ are identical.AA-TTTT L1核酸内切酶切割共有识别位点。*本整合位点无法被明确确定，原因是其伴随71bp的缺失且缺乏靶位点重复（TSD，Target Site Duplication）。本次标注的整合位点基于两种假设模型之一：其一为第二切口位于影响NF1有义链的第一切口的下游而非上游；其二为逆转录生成的Alu cDNA链（称为负链）入侵了给定整合位点下游71bp处的双链断裂位点。带有相同符号§、#或‡的整合位点为同一整合位点。