deo of Particle Manipulation Using a Programmable CMOS DEP Chip

Supplementary video for the article "A Programmable CMOS DEP Chip for Cell Manipulation" This video demonstrates the use of a CMOS DEP chip for particle manipulation, including particle patterning, concentration control, and single particle manipulation, all performed on the same chip and sample. This work presents a programmable DEP chip that allows dynamic reconfiguration of electric field patterns, enabling controlled particle movement on the chip surface. Implemented on a standard 0.18 µm CMOS process without post-processing, the chip features a 128 × 128 array of individually controllable 10 µm microelectrodes. The proposed electrode design enables particle manipulation at speeds up to 27 µm/s while operating at only 1.8 V. With its reconfigurability and biocompatibility, this low-voltage programmable CMOS DEP chip opens new possibilities in cell manipulation and analysis.《用于细胞操控的可编程CMOS介电电泳（dielectrophoresis, DEP）芯片》一文的补充视频 本视频展示了CMOS介电电泳芯片在微粒操控中的应用，涵盖微粒图案化、浓度调控以及单微粒操控三类操作，所有实验均在同一块芯片与样品上完成。 本研究提出一款可编程介电电泳芯片，可实现电场图案的动态重构，从而实现芯片表面微粒的可控移动。该芯片基于标准0.18 µm CMOS工艺制程制备，无需后处理工序，其核心为128×128阵列的独立可控10 µm微电极。 所提出的电极设计可实现最高27微米/秒的微粒操控速度，且仅需1.8 V的工作电压。凭借可重构性与生物相容性，这款低电压可编程CMOS介电电泳芯片为细胞操控与分析领域开辟了全新的应用可能。