RNA-seq of C. elegans reared on experimental microbiome (EM) and EM cell-free media against OP50-fed controls. RNA-seq of C. elegans reared on experimental microbiome (EM) and EM cell-free media against OP50-fed controls

We combined an experimental microbiome of 11 bacterial strains isolated from the gut of native Caenorhabditis elegans. C. elegans were maintained on the experimental microbiome, Escherichia coli OP50 (control food source), or OP50 supplemented with cell-free media (CFM) from the experimental microbiome. For each of the three feeding conditions, RNA-seq was performed for wildtype (N2) worms or transgenic worms expressing amyloid beta 1-42 in their body wall muscle (GMC101).