scRNA-seq and bulk RNA-seq analysis of normoxic and hyperoxic lung in mice [scRNA-seq]. scRNA-seq and bulk RNA-seq analysis of normoxic and hyperoxic lung in mice [scRNA-seq]

To explore the key molecules and mechanisms involved in the occurrence and development of BPD by using a hyperoxia-based BPD model in neonatal mice, providing new ideas for discovering new therapeutic target to approach the clinical prevention and treatment for BPD. Overall design: We performed single-cell RNA-seq (scRNA-seq) profiling analysis of whole lung cells from mice reared in normoxia or hyperoxia.