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Supplementary dataset 9 - The effects of model complexity and size on metabolic flux distribution and control. Case study in Escherichia coli.

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Zenodo2021-03-07 更新2026-05-25 收录
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9th part of Supplementary dataset 1-15: contains populations of 50'000 control coefficients (Metabolic Control Analysis) for three models D1, D2 and D3 of different network size. These populations of control coefficients were used to study the effects of model complexity - in terms of network size - on the conclusions drawn from MCA. A metric for measuring the sensitivity of MCA control coefficients to these structural changes was proposed.

补充数据集1-15的第9部分:包含对应3种不同网络规模的模型D1、D2与D3的50000组代谢控制分析(Metabolic Control Analysis)控制系数种群。该类控制系数种群被用于探究以网络规模为维度的模型复杂度对代谢控制分析(MCA)所得结论的影响。本研究同时提出了一种用于量化MCA控制系数对这类结构变化敏感性的指标。

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Zenodo
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2021-03-05
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