Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution

Protein Data Bank Japan2023-12-20 更新2026-03-21 收录

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Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution Descriptor: 1-(4-methoxy-1-methyl-indazol-3-yl)-3-(2-methoxyphenyl)urea, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, NICKEL (II) ION Authors: Cukier, C.D, Schnell, R, Lindqvist, Y, Schneider, G. Deposit date: 2013-05-17 Release date: 2013-09-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa Acs Chem.Biol., 8, 2013

本数据集为铜绿假单胞菌(Pseudomonas aeruginosa)来源的3-氧酰基-(酰基载体蛋白(acyl-carrier-protein))还原酶(3-oxoacyl-(acyl-carrier-protein) reductase, FabG)与1-(4-甲氧基-1-甲基吲唑-3-基)-3-(2-甲氧基苯基)脲形成复合物的晶体结构，解析分辨率为2.4埃（Å）。描述符：1-(4-甲氧基-1-甲基吲唑-3-基)-3-(2-甲氧基苯基)脲、3-氧酰基-[酰基载体蛋白]还原酶FabG、镍(II)离子作者：Cukier, C.D、Schnell, R、Lindqvist, Y、Schneider, G. 提交日期：2013-05-17 发布日期：2013-09-18 最后修改日期：2023-12-20 实验方法：X射线衍射(X-RAY DIFFRACTION)，分辨率2.4 Å 引用文献：《铜绿假单胞菌3-氧酰基-[酰基载体蛋白]还原酶的变构抑制剂结合位点的发现》，ACS Chem.Biol., 8, 2013

创建时间：

2013-05-17