Squamous cell carcinoma, metastatic, NOS - Female, 68 - Tissue image [3290730016638881]

This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 68Clinical description: A 68-year-old female patient was admitted to the Department of Pulmonology for the diagnosis of multiple in the lungs. CTscan: focal changes with spiculated outlines (27x23mm PP and 24x21mm PL) in both lungs- proliferative/inflammatory/? Moreover, infiltration in the abdominal cavity (inflammatory/hematoma/neo) in the right lateral (43x40x57mm). In addition, he reports increased dyspnea recently, weakness, decreased exercise tolerance, anemia, sweating, weight loss - about 3 kg in 2 months.

Translated with www.DeepL.com/Translator (free version)Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: SQUAMOUS CELL NEOPLASMSDiagnosis: Squamous cell carcinoma, metastatic, NOSResult of the histopathological examination: Sarcomatoid squamous cell carcinoma (CKAE1/AE3 +, vimentin +, CK7 +, CK20 -, CK5/6 + focal, p63 + focally, WT1 (-), podoplanin (-), calretinin (-), HMB45 (-), melanA (-), CD56 (-), CD34 (-), synaptophysin (-), TTF1 (-), CD99 (-), Bcl2 (-), caldesmon (-)). The surgical margin is positive.Sample:Material: FFPECollecting method: Surgical biopsyTopography: SKINOrgan: SKINTissue: Skin of trunkType of staining: positive/IHCStaining: Not applicableAntibody: CalretininTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存于ZMDL-GUMED的皮肤组织样本病理组织学图像。该样本图像采用Pannoramic 250 3DHistech病理切片扫描仪（放大倍数20倍）拍摄，并以DICOM格式存储。
患者、样本及诊断详细信息如下：
患者：年龄：68岁
临床描述：68岁女性患者因肺部多发病变就诊于肺科。CT扫描显示：双肺可见伴毛刺征的局灶性改变（PP区27×23mm、PL区24×21mm），考虑为增生性/炎性病变？待定。此外，右侧腹腔可见浸润性病灶（43×40×57mm，鉴别诊断为炎性病变/血肿/新生物）。近期该患者主诉呼吸困难加重、乏力、运动耐量下降、贫血、盗汗及体重下降（2个月内体重下降约3kg）。

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性别：女
诊断：
分类：ICD-O-3.2
分类编码：鳞状细胞肿瘤（SQUAMOUS CELL NEOPLASMS）
确诊诊断：转移性鳞状细胞癌，未特指（Squamous cell carcinoma, metastatic, NOS）
组织病理学检查结果：肉瘤样鳞状细胞癌（免疫组化标记结果：CKAE1/AE3阳性、波形蛋白（vimentin）阳性、CK7阳性、CK20阴性、CK5/6局灶阳性、p63局灶阳性、WT1阴性、podoplanin阴性、calretinin阴性、HMB45阴性、melanA阴性、CD56阴性、CD34阴性、突触素（synaptophysin）阴性、TTF1阴性、CD99阴性、Bcl2阴性、caldesmon阴性）。手术切缘阳性。
样本信息：
样本材质：福尔马林固定石蜡包埋组织（Formalin-Fixed Paraffin-Embedded, FFPE）
采集方式：手术活检
病变部位：皮肤
器官：皮肤
组织：躯干皮肤
染色类型：免疫组化（Immunohistochemistry, IHC）阳性
染色方案：无适用方案
所用抗体：Calretinin
成像技术与设备：Pannoramic 250 3DHistech
镜头放大倍数：20倍
机构来源：格但斯克医科大学（Medical University Gdańsk）