Data derived from Basse, Upper River Region studies.

Note: * Incidence per 100000 person-years. UUR, Upper River Region. CRR, Central River Region.†Person-years at risk in the placebo group is calculated from Enwere et al. (2006) in which there were 330 episodes of invasive bacterial infection in vaccine and placebo groups with overall incidence of 1009 per 100000 person-years [14]; 0.5× (330/1009×10−5) = 16501 person-years.‡The number of NTS isolates in the placebo group is calculated using the ratio of NTS incidence in placebo (300×10−5) versus vaccine (262×10−5) groups = 1.14 [14], and given 92 NTS isolates were detected in both groups. Thus, there were 49 NTS isolates in the placebo group (49/43 = 1.14 and 49+43 = 92).§The number of pneumococcal isolates in the placebo group is calculated using the incidence of IPD in placebo (453×10−5) versus vaccine (256×10−5) groups = 1.77 [14], and given 94 pneumococcal bloodstream isolates were detected in both groups. Thus, there were 60 pneumococcal isolates in the placebo group (60/34 = 1.77 and 60+34 = 94).∥NTS incidence calculated using age-specific incidence from Enwere et al., i.e. 2–5 mo: 408, 6–11 mo: 360, 12–17 mo: 334, 18–23 mo: 293, 24–29 mo: 42, 3–4 years: extrapolated as half the incidence among those 2 years of age, 42/2 = 21, **IPD incidence calculated from age-specific values [14], 2–5 mo: 363, 6–11 mo: 576, 12–17 mo: 526, 18–23 mo: 351, 24–29 mo: 339, 3–4 yrs: extrapolated as 339/2 = 170. Calculation of [14]: 0.71[(363/2)+(576/2)+(526/2)+(351/2)+339+170+170]/5 = 225.††authors' unpublished data.**备注：** * 每10万人年发病率。UUR为河流上游地区（Upper River Region），CRR为河流中游地区（Central River Region）。 † 安慰剂组的风险人年数源自Enwere等（2006）的研究：该研究中疫苗组与安慰剂组共发生330例侵袭性细菌感染，总发病率为1009/10万人年[14]；经计算：0.5×(330/1009×10^-5)=16501人年。 ‡ 安慰剂组的非伤寒沙门氏菌（NTS）分离株数量，通过安慰剂组与疫苗组的NTS发病率之比（300×10^-5 : 262×10^-5=1.14）[14]计算得出；已知两组共检出92株NTS分离株。因此安慰剂组含49株NTS分离株（满足49/43=1.14且49+43=92）。 § 安慰剂组的肺炎链球菌分离株数量，通过侵袭性肺炎链球菌病（IPD）在安慰剂组与疫苗组的发病率之比（453×10^-5 : 256×10^-5=1.77）[14]计算得出；已知两组共检出94株肺炎链球菌血流分离株。因此安慰剂组含60株肺炎链球菌分离株（满足60/34=1.77且60+34=94）。 ∥ NTS发病率采用Enwere等研究中的年龄特异性发病率计算：2–5月龄：408，6–11月龄：360，12–17月龄：334，18–23月龄：293，24–29月龄：42，3–4岁：按2岁以下人群发病率的一半外推，即42/2=21。 ** IPD发病率采用年龄特异性数值[14]计算：2–5月龄：363，6–11月龄：576，12–17月龄：526，18–23月龄：351，24–29月龄：339，3–4岁：按339/2外推得170。[14]的计算公式为：0.71×[(363/2)+(576/2)+(526/2)+(351/2)+339+170+170]/5=225。 †† 作者未公开数据。