Data from " Allostery can convert binding free energies into concerted domain motions in enzymes"

Data from " Allostery can convert binding free energies into concerted domain motions in enzymes" Electrophysiology data corresponding to the main text figures and supporting information figures. One representative set was chosen for each triplicate and included in this data set. For details are found in the ‘read me explanation.txt’ PDB used for this paper can be found at; 4ake [http://doi.org/10.2210/pdb4AKE/pdb] and 1ake [http://doi.org/10.2210/pdb1AKE/pdb] Full uncropped scans of any cropped gel/blot images are provided. The zip folder contains the MATLAB code package HMM inference, specifically tailored to nanopore ionic current flow data, as analyzed in the publication and can also be found at: https://github.com/yulanvanoppen/nanopore-HMM本数据集源自论文《变构效应可将结合自由能转化为酶的协同结构域运动》。 本数据集包含与正文图及补充信息图对应的电生理学数据。针对每一组三次重复实验，均选取一组代表性数据纳入本数据集，详细说明请参见‘read me explanation.txt’文件。 本文所用的蛋白质数据库（Protein Data Bank, PDB）条目可通过以下链接获取：4ake [http://doi.org/10.2210/pdb4AKE/pdb] 与 1ake [http://doi.org/10.2210/pdb1AKE/pdb]。 所有经裁剪的凝胶/印迹图像均提供完整的未裁剪扫描件。 本压缩包包含适配本论文中纳米孔离子流数据分析的隐马尔可夫模型（Hidden Markov Model, HMM）推理MATLAB代码包，该代码包也可通过以下链接获取：https://github.com/yulanvanoppen/nanopore-HMM