Recordings from three subregions of macaque prefrontal cortex during an information search and choice task

This dataset contains single unit recordings made from several different subregions of prefrontal cortex in 2 macaque monkeys (dorsolateral prefrontal cortex; orbitofrontal cortex; anterior cingulate cortex) performing an information search and decision-making task. Some of the neurons are simultaneously recorded across the different areas (during a typical recording session 8-24 electrodes were lowered simultaneously, see supplementary Table S1 in Hunt/Malalasekera et al., 2018). In the paper, we stack condition-averaged responses across the population to create pseudopopuluations, which reveal the distinct contributions of each PFC subregion to information search and reward-guided choice. Results from the experiments are described in: Triple dissociation of attention and decision computations across prefrontal cortex Laurence T. Hunt*, W.M. Nishantha Malalasekera*, Archy O. de Berker, Simon F. Farmer, Timothy E. J. Behrens and Steven W. Kennerley Nature Neuroscience in press (2018) doi: to be confirmed本数据集包含2只猕猴在执行信息搜索与决策任务时，从其前额叶皮层（prefrontal cortex）的多个不同亚区采集的单单位记录（single unit recordings），涉及的亚区包括背外侧前额叶皮层（dorsolateral prefrontal cortex）、眶额皮层（orbitofrontal cortex）以及前扣带回皮层（anterior cingulate cortex）。部分神经元可同时在不同脑区被记录：典型记录会话中会同时置入8-24根电极，详细信息参见Hunt/Malalasekera等人2018年研究的补充表S1。本研究中，我们通过堆叠群体的条件平均响应以构建伪群体（pseudopopulations），借此揭示各前额叶皮层亚区在信息搜索与奖励引导选择中发挥的独特作用。 本实验的相关结果已发表于： 《前额叶皮层注意力与决策计算的三重分离》（Triple dissociation of attention and decision computations across prefrontal cortex） 作者：Laurence T. Hunt*、W.M. Nishantha Malalasekera*、Archy O. de Berker、Simon F. Farmer、Timothy E. J. Behrens、Steven W. Kennerley 刊载于《Nature Neuroscience》（已录用，2018年），doi待确认。