Additional file 2: of Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individuals

Annotated data for the 3239 significantly differentially methylated CpG sites between omental and abdominal subcutaneous adipose after weight loss. Illumina probe ID, gene name, gene region and chromosomal location (as Illumina 450K manifest) are shown along with methylation statistics. OM_mean_beta and AB_mean_beta present mean beta values for omental (OM) and abdominal subcutaneous (AB) adipose, respectively. We also indicate which CpG sites overlap with those observed in the post-weight loss analysis (Overlap_CpG), whether the change in methylation between SC and OM is greater at the post-weight loss time point (Greater_Δbeta_Post) and whether the CpG site was observed as differentially methylation before vs after weight loss in AB (Overlap_AB_Benton_etal) and OM (Overlap_OM_Benton_etal) in our previous study [37]. (CSV 637 kb)本数据集收录了减肥后大网膜脂肪（omental adipose）与腹部皮下脂肪（abdominal subcutaneous adipose）之间的3239个经注释的显著差异甲基化CpG位点。数据集同步提供Illumina探针ID、基因名、基因区域及染色体位置（遵循Illumina 450K芯片注释手册（Illumina 450K manifest）），并附带甲基化统计数据。其中OM_mean_beta与AB_mean_beta分别对应大网膜脂肪（OM）与腹部皮下脂肪（AB）的平均β值（beta value）。此外，数据集还额外标注了如下信息：与减肥后分析中检出的CpG位点存在重叠的位点（Overlap_CpG）、减肥后时间点下皮下脂肪与大网膜脂肪间的β值变化是否更大（Greater_Δbeta_Post），以及该CpG位点是否在本团队此前研究[37]的腹部皮下脂肪（对应字段Overlap_AB_Benton_etal）与大网膜脂肪（对应字段Overlap_OM_Benton_etal）样本中，被观测到存在减肥前后的差异甲基化。本数据集为CSV格式，文件大小637KB。