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Effect of BET Inhibitors on Rheumatoid Synovial Fibroblast Cells [ChIP-seq]

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NIAID Data Ecosystem2026-03-12 收录
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We demonstrate that JQ1 inhibits IL1B based RA Synovial Fibroblast activation and proliferation, by inhibiting key BRD2/4 superenhancer genes. Overall design: FLS cells pre and post JQ1 treatment; associated ChIP-Seq of POL2, BRD2, and BRD4.

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2020-12-16
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