The destruction of articular cartilage in osteoarthritis involves chondrocyte dysfunction and imbalanced extracellular matrix (ECM) homeostasis. Pro-inflammatory cytokines such as interleukin-1α (IL-1
“-”, not applicable. Mean and standard deviation were calculated using Microsoft Excel. Twelve replicates were set up for each protein/nucleant combination tested, therefore the maximum possible numbe
A): in the absence of crystallization agents; B): in the presence of crystallization agents. Lys.: lysozyme; Pro. K: proteinase K; Chy. A: α-chymotrypsinogen A (II); Con. A: concanavalin A.