Who is engaging with lateral flow testing for COVID-19 in the UK? The COVID-19 Rapid Survey of Adherence to Interventions and Responses (CORSAIR) study

Objectives: To investigate uptake of lateral flow testing, reporting of test results and psychological, contextual and socio-demographic factors associated with testing.Design: A series of four fortnightly online cross-sectional surveys.Setting: Data collected from 19 April 2021 to 2 June 2021.Participants: People living in England and Scotland, aged 18 years or over, excluding those who reported their most recent test was a polymerase chain reaction (PCR) test (n=6646, n≈1600 per survey).Main outcome measures: Having completed at least one lateral flow test (LFT) in the last 7 days.Results: We used binary logistic regressions to investigate factors associated with having taken at least one LFT. Increased uptake of testing was associated with being vaccinated (adjusted ORs (aORs)=1.52–2.45, 95% CI 1.25 to 3.07, analysed separately by vaccine dose), employed (aOR=1.94, 95% CI 1.63 to 2.32), having been out to work in the last week (aOR=2.30, 95% CI 1.94 to 2.73) and working in a sector that adopted LFT early (aOR=2.54, 95% CI 2.14 to 3.02) . Uptake was higher in people who reported cardinal COVID-19 symptoms in the last week (aOR=1.89, 95% CI 1.34 to 2.66). People who had heard more about LFTs (aOR=2.28, 95% CI 2.06 to 2.51) and knew they were eligible to receive regular LFTs (aOR=2.98, 95% CI 2.35 to 3.78) were also more likely to have tested. Factors associated with not taking a test included agreeing that you do not need to test for COVID-19 unless you have come into contact with a case (aOR=0.51, 95% CI 0.47 to 0.55).Conclusions: Uptake of lateral flow testing is low. Encouraging testing through workplaces and places of study is likely to increase uptake, although care should be taken not to pressurise employees and students. Increasing knowledge that everyone is eligible for regular asymptomatic testing and addressing common misconceptions may drive uptake.

研究目标：探究侧向流检测（lateral flow testing, LFT）的接受率、检测结果报告情况，以及与检测相关的心理、情境及社会人口学因素。
研究设计：四项每两周开展一次的在线横断面调查系列研究。
研究实施场景：数据采集于2021年4月19日至2021年6月2日期间完成。
研究对象：英格兰与苏格兰地区年满18周岁的常住居民，排除自述近期末次检测为聚合酶链式反应（polymerase chain reaction, PCR）检测的人群，最终有效样本量为6646例，每项调查约纳入1600名参与者。
主要结局指标：过去7天内完成至少1次侧向流检测（lateral flow testing, LFT）。
结果：本研究采用二元logistic回归（binary logistic regression）分析与至少完成1次侧向流检测相关的影响因素。检测接受率提升与以下因素显著相关：完成疫苗接种（按疫苗剂次分别分析，校正优势比（adjusted odds ratio, aORs）为1.52~2.45，95%置信区间[CI]为1.25~3.07）、处于在职状态（aOR=1.94，95%CI=1.63~2.32）、过去一周有外出工作经历（aOR=2.30，95%CI=1.94~2.73），以及就职于早期推广LFT的行业（aOR=2.54，95%CI=2.14~3.02）。过去一周出现新冠典型症状的人群检测接受率更高（aOR=1.89，95%CI=1.34~2.66）。对LFT知晓程度更高的人群（aOR=2.28，95%CI=2.06~2.51）以及知晓自身符合定期接受LFT资格的人群（aOR=2.98，95%CI=2.35~3.78）同样更有可能完成检测。与未接受检测相关的因素包括认同‘仅在接触新冠病例时才需进行新冠检测’这一观点（aOR=0.51，95%CI=0.47~0.55）。
结论：侧向流检测的接受率仍处于较低水平。通过工作场所与学习场所推广检测或可提升接受率，但需注意避免给员工与学生施加不必要的压力。提升大众对全体人群均可定期接受无症状检测的认知，并纠正常见认知误区，或可推动检测接受率的提升。