Comparative within-subjects serum and plasma protein levels in pregnant women

Paired serum and plasma samples were obtained from biorepositories of a multinational prospective cohort study on maternal and fetal outcomes. Samples analyzed were collected during an initial visit (gestational weeks [GWs] 8-19) and on a subsequent visit (GWs 24-28). A total of 88 paired were analyzed. Fifty-six women contributed one paired sample collected during the first or second visit, while 16 women contributed two paired samples collected on subsequent study visits.  Plasma and serum samples were analyzed with a highly multiplexed platform using proximity extension technology for quantifying 1,161 proteins (Olink Proteomics Inc., Watertown, MA). 

The file contains the following seven columns: (A) Subject ID, (B) Visit number, (C) Gestational age at the time of sampling, (D) Protein name, (E) Uniprot ID, (F) Protein serum level (NPX), and (G) Protein plasma level (NPX).