Supplementary figures: The impact of socioeconomic crisis on cancer patient outcomes in Lebanon, 2018–2020

These are peer-reviewed supplementary materials for the article 'The impact of socioeconomic crisis on cancer patient outcomes in Lebanon, 2018–2020' published in the Journal of Comparative Effectiveness Research.Figure 1: Probability of survival for breast cancer before in (1 red) and after (2 green) crisisFigure 2: Probability of survival for renal cancer before in (1 red) and after (2 green) crisisFigure 3: Probability of survival for lung cancer before in (1 red) and after (2 green) crisisAim: The goal of this study was to assess the impact of economic and social crisis on access to cancer care in Lebanon. Materials & methods: A cancer Drug Access Program in Lebanon was launched, covering 80–90% of treatment costs. The program included three drugs for breast cancer, renal cancer, and lung cancer. A longitudinal follow-up of patients was conducted. The Multidimensional Poverty Measure (MPI) was used by year (2019 or 2021), i.e., before and after the onset of the economic crisis. Results: A total of 613 cancer patients were included in 50 hospitals.Mean patient age was 58.5 years (standard deviation = 12.3). The proportion of cancer types was 79.3% breast, 10.6% renal, and 7.3% lung cancer. Treatment with palbociclib (hazard ration [HR]: 1.64; 95% confidence interval [CI]: 1.53–1.76, p Conclusion: Economic crises have negative impacts on health outcomes, andwe identified a change in survival pre/post crisis onset. This study argues strongly for coordinated efforts to mitigate the negative effects of poverty on health.本材料为发表于《比较效果研究杂志（Journal of Comparative Effectiveness Research）》的论文《2018-2020年黎巴嫩社会经济危机对癌症患者结局的影响》的同行评议补充资料。 图1：乳腺癌患者在危机前（红色曲线1）与危机后（绿色曲线2）的生存概率 图2：肾癌患者在危机前（红色曲线1）与危机后（绿色曲线2）的生存概率 图3：肺癌患者在危机前（红色曲线1）与危机后（绿色曲线2）的生存概率 研究目的：本研究旨在评估黎巴嫩经济与社会危机对癌症诊疗可及性的影响。 材料与方法：黎巴嫩启动了一项癌症药物可及性项目，覆盖80%~90%的治疗费用。该项目涵盖针对乳腺癌、肾癌与肺癌的三种治疗药物。研究对患者开展了纵向随访，并按危机爆发前后的年份（2019年即危机前，2021年即危机后）采用多维贫困指数（Multidimensional Poverty Measure, MPI）进行评估。 结果：本研究共纳入50家医院的613名癌症患者。患者平均年龄为58.5岁（标准差=12.3）。癌症类型占比分别为乳腺癌79.3%、肾癌10.6%、肺癌7.3%。接受哌柏西利（palbociclib）治疗的患者风险比（hazard ratio, HR）为1.64；95%置信区间（confidence interval, CI）为1.53~1.76，p 结论：经济危机对健康结局存在负面影响，我们明确了危机爆发前后患者生存率的变化情况。本研究强烈呼吁开展协同行动，以减轻贫困对健康带来的不利影响。