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Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations

NIAID Data Ecosystem2026-05-02 收录

蛋白质定向进化

酶工程突变

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https://www.rcsb.org/structure/4HHQ 数据链接链接失效反馈

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Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations

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创建时间：

2024-11-20

蛋白质定向进化

合成生物文库设计

CDR’ refers to a degenerate codon with the following nucleotide frequencies: 20% A, 15% C, 25% G, and 40% T at site 1, 50% A, 25% C, 15% G, and 10% T at site 2, and 0% A, 45% C, 10% G, and 45% T at si

NIAID Data Ecosystem30

Table1_Binding pocket stabilization by high-throughput screening of yeast display libraries.DOCX

蛋白质定向进化

高通量药物筛选

Protein dynamics have a great influence on the binding pockets of some therapeutic targets. Flexible protein binding sites can result in transient binding pocket formation which might have a negative

NIAID Data Ecosystem10

A Robust and Versatile Method of Combinatorial Chemical Synthesis of Gene Libraries via Hierarchical Assembly of Partially Randomized Modules

组合基因库合成

蛋白质定向进化

A major challenge in gene library generation is to guarantee a large functional size and diversity that significantly increases the chances of selecting different functional protein variants. The use

Figshare2016-01-15 更新10

Structure-augmented MLDE

蛋白质定向进化

结构增强机器学习

Supplementary Files for Structure-augmented MLDE for GB1

Zenodo2024-02-27 更新20

Lucilia cuprina alpha esterase 7 directed evolution round 8

蛋白质定向进化

昆虫抗药性

Lucilia cuprina alpha esterase 7 directed evolution round 8 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ACETATE ION, ... Authors: Frkic, R.L, Fraser, N, Mabbitt, P.D, Jackson, C.J. Depo

Protein Data Bank Japan2026-03-04 更新10

Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations

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