Single-cell whole genome sequencing data from three mouse (C57BL/6) lymphocytes

Single-cell whole genome sequencing data from three selected mouse (C57BL/6) lymphocytes from Rohrback et al. 2018 PNAS paper 'Submegabase copy number variations arise during cerebral cortical neurogenesis as revealed by single-cell whole-genome sequencing'.This project contains the following:1. bams/├── SRR6204878_sra.bai├── SRR6204878_sra.bam├── SRR6204878_sra.bam.md5├── SRR6204923_sra.bai├── SRR6204923_sra.bam├── SRR6204923_sra.bam.md5├── SRR6204925_sra.bai├── SRR6204925_sra.bam└── SRR6204925_sra.bam.md5(aligned to GRCm38/mm10 genome)2. scan2_out/├── gatk│ ├── hc_raw.mmq60.vcf.gz│ └── hc_raw.mmq60.vcf.gz.tbi└── shapeit├── phased_hets.vcf.gz└── phased_hets.vcf.gz.tbi<br>(Simulated hetSNP and phasing information)<br>mappability/100mer.chr*.txt(Match mappability tracks required by HiScanner)<br>

本数据集取自Rohrback等学者2018年发表于《美国国家科学院院刊》（PNAS）的研究论文《单细胞全基因组测序揭示大脑皮层神经发生过程中出现亚兆碱基级拷贝数变异》，包含3株经筛选的C57BL/6小鼠淋巴细胞的单细胞全基因组测序（single-cell whole genome sequencing）数据。
本项目包含以下内容：
1. bams/目录：
├── SRR6204878_sra.bai
├── SRR6204878_sra.bam
├── SRR6204878_sra.bam.md5
├── SRR6204923_sra.bai
├── SRR6204923_sra.bam
├── SRR6204923_sra.bam.md5
├── SRR6204925_sra.bai
├── SRR6204925_sra.bam
└── SRR6204925_sra.bam.md5
（所有文件均比对至GRCm38（mm10）小鼠参考基因组）
2. scan2_out/目录：
├── gatk
│ ├── hc_raw.mmq60.vcf.gz
│ └── hc_raw.mmq60.vcf.gz.tbi
└── shapeit
├── phased_hets.vcf.gz
└── phased_hets.vcf.gz.tbi
（包含模拟的杂合单核苷酸多态性（hetSNP）与单体型相位信息）
3. mappability目录下的100mer.chr*.txt文件，用于匹配HiScanner所需的比对度轨迹文件