Summary statistics for genetic instruments used in multivariable MR analyses.

SNP: rsID of genetic instrument; expZ: trait and data set used as first/second/… exposure (e.g., if exp1 is ldl_mvp, LDL summary statistics from GLGC were used as the first exposure); expZ_beta: effect size estimate for trait expZ; expZ_se: standard error of effect size estimate for trait expZ; expZ_pval: P-value of effect size estimate for trait expZ; bc_beta: BC risk effect size estimate; bc_se: standard error of BC effect size estimate; bc_pval: P-value of BC effect size estimate; test: unique identifier for each 2, 3, or 5-exposure MVMR experiment included in this table. AaM, age at menarche; BC, breast cancer; BMI, body mass index; GLGC, Global Lipids Genetics Consortium; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MR, Mendelian randomization; MVMR, multivariable MR; MVP, Million Veteran Program; TC; total cholesterol; TG, triglyceride. (XLSX)