We produced shotgun bisulfite sequencing (SBS) data from single murine female primordial germ cells and fully-grown oocytes by an improved multiplexing and amplification-free post bisulfite adapter ta

NIAID Data Ecosystem60

Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis (MeDIP-seq)

生殖细胞表观遗传学

精原细胞分化

Background: Spermatogonial stem cells (SSCs) sustain the process of steady-state spermatogenesis in the mammalian testis, which is critical to the ongoing production of sperm and male fertility. SSCs

NIAID Data Ecosystem70

Sequential enhancer state remodelling defines human germline competence and specification [ULI-NChIP-seq]. Sequential enhancer state remodelling defines human germline competence and specification [ULI-NChIP-seq]

生殖细胞表观遗传学

增强子互作网络

Germline-soma segregation is a fundamental event during mammalian embryonic development. Here we establish the epigenetic principles of human primordial germ cell (hPGC) development using in vivo hPGC

NIAID Data Ecosystem60

Loss of the Mili-interacting Tdrd1 activates transposons and alters Mili-associated small RNA profile

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