Anti-PrPSc activity and cytotoxicity of DB772 in sheep microglial cells and Rov cells.

a50% tissue culture effective concentration (TCEC50). Values are the range in one independent experiment; two additional independent experiments confirmed the value was less than .4 μM. bValues are the mean ± one standard deviation of three independent experiments. c50% cytotoxic concentration (CC50). Values are the mean ± one standard deviation of four independent experiments. dNot determined. eNot applicable as no anti-PrPSc activity was measured.