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Interferon-alpha signaling promotes AGM HSC maturation

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70878
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Interferon-alpha promotes engraftment of mid-gestation hematopoietic stem cells by promoting competitiveness and restore the hematopoietic defect of Arid3a knockout embryos We used microarray to response of AGM HSCs (VE+CD45+) to IFNa (0.5ng/ml) treatment for 4 hours Isolated VE+CD45+ cells from E11.5 AGM were treated with IFNa (0.5ng/ml) in 10% FBS/IMDM for 4 horus before RNA isolation. RNA was NuGen amplified.
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2019-02-11
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