Additional file 5 of Immunogenicity of monkeypox virus surface proteins and cross-reactive antibody responses in vaccinated and infected individuals: implications for vaccine and therapeutic development

Supplementary Material 5: Table S1. Basic information of complete genome sequences in phylogenetic tree. Table S2. Factors associated with the seropositivity of antibody and VACV neutralization capacity in all groups (sex, MPXV infection, VACV vaccinated and age) Table S3. Factors associated with the seropositivity of antibody and VACV neutralization capacity in MPXV-infected individuals (MXPV CT value, CD4 + count, CD4 + /CD8 + and HIV viral load). Table S4. MPXV antigen amino acid similarity within OPXVs. CI,confidence interval; EC50, Median effect concentration; HIV, Human immunodeficiency virus; ID50, 50% inhibitory dilutions; MPXV, Monkeypox virus; OPXV, Orthopoxvirus; SPXV, Smallpox virus; TT, Tiantan; VACV, Vaccinia virus; WR, Western Reserve.补充材料5：表S1。系统发育树中完整基因组序列的基本信息。表S2。所有组别中抗体血清阳性率与痘苗病毒（Vaccinia virus, VACV）中和能力相关的影响因素（性别、猴痘病毒（Monkeypox virus, MPXV）感染史、VACV疫苗接种史及年龄）。表S3。猴痘病毒（Monkeypox virus, MPXV）感染个体中抗体血清阳性率与VACV中和能力相关的影响因素（MPXV CT值、CD4+细胞计数、CD4+/CD8+比值及人类免疫缺陷病毒（Human immunodeficiency virus, HIV）病毒载量）。表S4。正痘病毒（Orthopoxvirus, OPXV）属内猴痘病毒抗原的氨基酸相似性。缩写注释：置信区间（Confidence Interval, CI）；半数效应浓度（Median Effect Concentration, EC50）；人类免疫缺陷病毒（Human Immunodeficiency Virus, HIV）；50%抑制稀释度（50% Inhibitory Dilutions, ID50）；猴痘病毒（Monkeypox virus, MPXV）；正痘病毒（Orthopoxvirus, OPXV）；天花病毒（Smallpox virus, SPXV）；天坛株（Tiantan, TT）；痘苗病毒（Vaccinia virus, VACV）；西储备株（Western Reserve, WR）