Ubiquitin is a tag that often initiates degradation of proteins by the proteasome in the ubiquitin proteasome system. Targeted expression of K6W mutant ubiquitin (K6W-Ub) in the lens results in defect
This study is to characterize the molecular components that could contribute to the formation of lens extracellular diffusion barrier. Three regions were isolated from lens cortex using laser capture
Differentiation of pluripotent stem cells into lentoid bodies is important for the understanding of the lens development and investigating the processes critical for lens morphogenesis. This Study was
Mice with deletion of genes for small heat shock proteins αA- and αB-crystallin (αA/αB–/–) develop cataracts. We used proteomic analysis to identify lens proteins that change in abundance after deleti