five

Translation efficiency in the mouse liver upon 24h fasting

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP437269
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To investigate the translatome in the fasted condition and the role of phosphoralated eIF4E in it We performed polysome sequencing on fed and fasted wild type mice and fasted eIF4E S209A/S209A mice Overall design: We seperated highly translated mRNA and low translated mRNA using sucrose gradient and perform comparative gene expression profiling analysis of RNA-seq data for those high tanslated and low translated mRNA from fed and fasted WT livers, and fasted eIF4E S209A/S209A livers
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2024-09-13
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