An Efficient Route to Tetrahydroindeno[2,1-b]pyrroles via a Base-Promoted Reaction of (E)-2-Alkynylphenylchalcone with 2-Isocyanoacetate

A base-promoted cascade reaction of (E)-2-alkynylphenylchalcone with 2-isocyanoacetate provides a novel and efficient route for the synthesis of tetrahydroindeno[2,1-b]pyrroles. The reaction proceeds smoothly in air under mild conditions with high efficiency.(E)-2-炔基苯基查尔酮与2-异氰乙酸酯的碱促进级联反应，为四氢茚并[2,1-b]吡咯的合成提供了一种新颖高效的途径。该反应可在空气氛围、温和条件下顺利进行，且具有优异的反应效率。