Improvement of prediction of all-cause death by biomarkers.

CI = confidence interval; SD = standard deviation; WHtR = waist-to-height-ratio; HbA1c = hemoglobin A1c; IGF-1 = Insulin-like growth factor 1; hsCRP = high-sensitive C-reactive protein. Conventional risk factors include age, sex, systolic blood pressure, high-density lipoprotein cholesterol, total cholesterol, antihypertensive medication, diabetes, and current smoking.*For conventional cardiovascular risk factors only or conventional cardiovascular risk factors + biomarkers.置信区间（confidence interval, CI）；标准差（standard deviation, SD）；腰围身高比（waist-to-height-ratio, WHtR）；糖化血红蛋白（hemoglobin A1c, HbA1c）；胰岛素样生长因子1（Insulin-like growth factor 1, IGF-1）；高敏C反应蛋白（high-sensitive C-reactive protein, hsCRP）。传统心血管危险因素涵盖年龄、性别、收缩压、高密度脂蛋白胆固醇、总胆固醇、降压用药情况、糖尿病史及当前吸烟状态。*仅针对传统心血管危险因素，或传统心血管危险因素联合生物标志物。