File S1 - Membrane Orientation and Binding Determinants of G Protein-Coupled Receptor Kinase 5 as Assessed by Combined Vibrational Spectroscopic Studies
Hydrophobic contacts are given as average number of contacts per frame. Hydrogen bonds and cation-π occupancies are shown in percentages. Residues in bold indicate hydrogen bonds involving the amino a
NMR data-driven model of GTPase KRas-GDP tethered to a lipid-bilayer nanodisc Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... Authors: Mazhab-Jafari, M, Stat
Simulations of a single copy of the PKC alpha C2 domain (PDB:1DSY) with a lipid membrane consisting of 40 POPS and 160 POPC molecules. The system is solvated by 20000 water molecules (100 per lipid),
Mitochondrial apoptosis is a programmed suicide mechanism in cells essential for life. Upon oxidative stress, the mitochondrial outer membrane (MOM) undergoes permeabilization, followed by the release
Synaptotagmin (Syt) is a membrane-associated protein involved in vesicle fusion through the SNARE complex that is found throughout the human body in 17 different isoforms. These isoforms have two memb
