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Role of LRRK2 in murine intestinal macrophages
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创建时间：
2022-01-09
相关数据集
Supporting data for "Pathogenic mutant LRRK2 R1441G in mitochondrial dysfunction and synucleinopathy in Parkinson’s disease"
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder. Disease hallmarks include deposition of misfolded α-synuclein (αSyn) aggregates and mitochondrial dysfunction that ind
DataCite Commons2023-08-25 更新70
Analytes discriminating between LRRK2 mutation carriers and Controls.
Analytes are defined by their retention time and dominant channel in LCECA profiles. + up-regulated in LRRK2 mutation carriers; − down-regulated in LRRK2 mutation carriers.
NIAID Data Ecosystem50
Cytokine secretion in wild type and LRRK2 KO BMDM’s following LPS stimulation.
Bone marrow derived macrophages from LRRK2 knockout mice and wild type littermate controls were plated at a density of 1×106 in 2 ml of tissue culture media. Cells were treated with 100 ng/ml LPS 24 h
NIAID Data Ecosystem30
Cytokine secretion in wild type and LRRK2 KO BMDM’s following PAM3CSK4 stimulation.
Bone marrow derived macrophages from LRRK2 knockout mice and wild type littermate controls were plated at a density of 1×106 in 2 ml of tissue culture media. Cells were treated with 1 µg/ml Pam3CSK4 2
NIAID Data Ecosystem50
Figure 4 tabular data for the paper Development of LRRK2 designed ankyrin-repeat proteins
Figure 4 tabular data for 1) GFP-LRRK2 filamentation assay in HEK293T cells in the presence or absence of DARPin E11 2) westernblot analysis of pRab8/total GFP-Rab8 signal in the presence or absence
NIAID Data Ecosystem30
