Urinary pyrimidine concentrations and DPYS genotypes in the family of the patient with severe 5-FU toxicity.

a Kouwaki et al. Clinical Cancer Research, 4: 2999–3004 (1998) [27]b wt, wild-typecc.1001A>G was in cis with common synonymous variant c.216C>T (p.F72F).Urinary pyrimidine concentrations and DPYS genotypes in the family of the patient with severe 5-FU toxicity.a Kouwaki 等人，《临床癌症研究（Clinical Cancer Research）》，第4卷：2999–3004（1998年）[27] b wt，野生型（wild-type） c.1001A>G 与常见同义变异 c.216C>T（p.F72F）处于顺式连锁状态。 严重5-氟尿嘧啶（5-FU）毒性患者家系的尿液嘧啶浓度与DPYS基因型。