Staphylococcus aureus Dihydrofolate reductase in complex with NADPH and Methotrexate
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Staphylococcus aureus Dihydrofolate reductase in complex with NADPH and Methotrexate Descriptor: Dihydrofolate reductase, GLYCEROL, METHOTREXATE, ... Authors: Reeve, S.M, Wright, D.L. Deposit date: 2019-06-10 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin ResistantStaphylococcus aureus. Acs Infect Dis., 5, 2019
与烟酰胺腺嘌呤二核苷酸磷酸(NADPH)和甲氨蝶呤(Methotrexate)结合的金黄色葡萄球菌(Staphylococcus aureus)二氢叶酸还原酶(Dihydrofolate reductase) 描述符:二氢叶酸还原酶、甘油(GLYCEROL)、甲氨蝶呤(METHOTREXATE)等 作者:Reeve, S.M.、Wright, D.L. 提交日期:2019-06-10 发布日期:2019-10-23 最后修改日期:2023-10-11 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.86埃(1.86 Å) 引用文献:《针对从耐甲氧西林金黄色葡萄球菌(Methicillin Resistant Staphylococcus aureus)临床分离株中鉴定出的耐甲氧苄啶(Trimethoprim)酶的广谱二氢叶酸还原酶抑制剂研究》,刊载于《ACS感染性疾病》(Acs Infect Dis.),2019年,第5卷



