Frequency (that is, proportion of incidences) of each of the six types of cell shape division outcome over the entire cell lineages analysed for the sixteen curved mutants and the wild-type.

Measurements are based on the phenotype of progenitors and progeny before cell septation. 1–6 are represented in Fig. 1D. The columns on the right indicate the measured penetrance at septation (left) and predicted penetrance at septation (by the Markovian model) based on the six frequencies (right), for each mutant. Importantly, the measured penetrances and the frequencies come from independent biological experiments. For all strains other than alp14Δ and pom1Δ both penetrances were within ±5% difference. This likely due to the fact that alp14Δ cells often do not undergo division (not shown) and that pom1Δ cells divide highly asymmetrically [18], both features which are not accounted for by our model.Frequency (that is, proportion of incidences) of each of the six types of cell shape division outcome over the entire cell lineages analysed for the sixteen curved mutants and the wild-type.本测量基于细胞隔膜形成前的祖代与子代细胞表型。1~6类表型已在图1D中呈现。针对各突变体，右侧列分别标注了隔膜形成时的实测外显率，以及基于六种发生频率、通过马尔可夫模型预测得到的隔膜形成时外显率。值得注意的是，实测外显率与发生频率来自独立的生物学实验。除alp14Δ与pom1Δ突变株外，其余所有菌株的两种外显率差值均处于±5%以内。该偏差可能源于alp14Δ细胞通常无法完成分裂（数据未展示），以及pom1Δ细胞分裂高度不对称[18]，而本模型未涵盖上述两种特征。本数据集统计了16株弯曲形态突变体与野生型菌株的全细胞谱系中，六种细胞形态分裂结局的发生频率（即事件发生占比）。