Effect of EGFR activation on mouse chondrocytes. Effect of EGFR activation on mouse chondrocytes
收藏NIAID Data Ecosystem2026-03-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA450631
下载链接
链接失效反馈官方服务：
资源简介：
We examined the change of chondrocyte transcriptome after EGFR activation by TGF-α and inhibition by gefitinib. Data analysis showed that EGFR activation down-regulates cartilage ECM biosynthesis and promotes ECM degradation. Gefitinib can reverse the effects of EGFR on chondrocytes. Overall design: Cells: P2 mouse epiphyseal chondrocytes; Groups: Control (PBS), TGF-α (10 ng/ml, 48 h), TGF-α + Gefitinib (10 μM, 48 h)
创建时间：
2018-04-17
