Reducing cholesteol in macrophages alters epigemone. Reducing cholesteol in macrophages alters epigemone

Cholesterol reduction in macrophages by methyl-beta-cyclodextran (MCD) alters gene expression and genomic configuration in a cholesterol specific fashion. Overall design: ATAC-seq was performed on RAW macrophages, treated with MCD (5 mM, 1 hour) or without. Two replicates were performed for untreated control (ctl); two replicastes for MCD treated cells MCD).