Genome-wide analysis of ATF4 binding in histidinol-treated cells
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https://www.ncbi.nlm.nih.gov/sra/SRP058782
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资源简介：
Activating Transcription Factor 4 (ATF4) is a transcription factor induced by the integrated stress response (ISR). This experiment is a genome-wide occupancy profiling of ATF4 in human HAP1 cells. HAP1 is a near-haploid human cell line that was derived from KBM-7 cells isolated from a patient with Chronic Myelogenous Leukemia. We induced ATF4 expression by mimicking amino acid starvation with the drug histidinol. We identified peaks of ATF4 binding using three independent antibodies. Overall design: Examination of ATF4 binding in HAP1 cells treated with 2 mM histidinol for 24 hours.
创建时间：
2020-02-24
