Supplementary Table S2: Sig3 scores and FGA values in LMS tumor samples. Sig3+ samples are predicted with a classifier trained in WGS LMS data. FGA values are calculated on CNVkit-based copy number pr
Ultraviolet (UV) light induces the formation of bulky UV photoproducts in the genome that interfere with DNA replication and transcription. It is well-established how human cells repair UV light-induc
Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that