Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP
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Crystal structure of a mutant of the large fragment of DNA polymerase I from thermus aquaticus in a closed ternary complex with DNA and ddCTP Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... Authors: Schnur, A, Marx, A, Welte, W, Diederichs, K. Deposit date: 2010-12-12 Release date: 2011-06-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity. Chembiochem, 12, 2011
水生嗜热菌(Thermus aquaticus)来源的DNA聚合酶I(DNA polymerase I)大片段突变体与DNA及ddCTP形成封闭三元复合物的晶体结构
组分:2',3'-双脱氧胞苷5'-三磷酸(2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE)、DNA(5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3')、DNA(5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'),……
作者:Schnur A、Marx A、Welte W、Diederichs K
沉积日期:2010年12月12日
发布日期:2011年6月15日
最后修改日期:2024年2月21日
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.74埃(Å)
引用文献:《Learning from Directed Evolution: Thermus aquaticus DNA Polymerase Mutants with Translesion Synthesis Activity》,发表于《Chembiochem》,2011年,第12卷
创建时间:
2010-12-12



