Additional file 9 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

Additional file 9: Table S5. Results of the EWAS of metabolite measure principal components. Presented are the statistically significant (Bonferroni-adjusted P < 1.34e−8) results of the EWAS of the first 8 principal components of the metabolite measures data in the discovery cohort KORA F4. CHR: annotated chromosome of the CpG site; Pos: annotated chromosomal position of the CpG site; Coef: coefficient of the CpG site in the regression model; SE: standard error of the coefficient; P: p value; PC_explained_var: Explained variance of the metabolite principal component.

补充材料9：附表S5。本附表呈现代谢物测量主成分的全表观基因组关联研究（Epigenome-Wide Association Study，EWAS）结果。具体展示了在发现队列KORA F4中，针对代谢物测量数据的前8个主成分开展EWAS分析所得的经Bonferroni校正后P值小于1.34×10^-8的统计学显著结果。各字段说明如下：CHR：注释的CpG位点（CpG site）所在染色体；Pos：注释的CpG位点的染色体位置；Coef：回归模型中CpG位点的回归系数；SE：系数的标准误；P：P值；PC_explained_var：代谢物主成分的解释方差。