Association of the FTO, MC4R and the combined score (FTO and MC4R polymorphisms) with obesity. Stratified multivariate* logistic regression analysis according to physical activity.

*: Models adjusted for sex, age, center, diabetes, total energy intake and leisure time physical activity.**: For the estimation of the variante allele efects a variable indicating the number of variant alleles (0, 1 or 2) was created for FTO and MC4R.***: For the estimation of the variant allele effect of the aggregate score a variable indicating the number of combined variant alleles (0, 1, 2, 3 or 4) was created.P1: P-value obtained for the global effect of the polymorphism in the multivariate logistic regression models.P2: P-value for the interaction term between physical activity polymorphism and the corresponding polymorphism in the logistic regression model.CI: Confidence interval.