Association of the FTO, MC4R and the combined score (FTO and MC4R polymorphisms) with obesity. Stratified multivariate* logistic regression analysis according to physical activity.

*: Models adjusted for sex, age, center, diabetes, total energy intake and leisure time physical activity.**: For the estimation of the variante allele efects a variable indicating the number of variant alleles (0, 1 or 2) was created for FTO and MC4R.***: For the estimation of the variant allele effect of the aggregate score a variable indicating the number of combined variant alleles (0, 1, 2, 3 or 4) was created.P1: P-value obtained for the global effect of the polymorphism in the multivariate logistic regression models.P2: P-value for the interaction term between physical activity polymorphism and the corresponding polymorphism in the logistic regression model.CI: Confidence interval.*：针对性别、年龄、研究中心、糖尿病状态、总能量摄入及休闲时间体力活动进行校正的模型。 **：为估算变异等位基因（variant allele）效应，针对FTO和MC4R基因构建了用于表示变异等位基因数目（0、1或2）的变量。 ***：为估算综合评分的变异等位基因效应，构建了用于表示联合变异等位基因数目（0、1、2、3或4）的变量。 P1：多因素logistic回归模型中，基因多态性全局效应对应的P值。 P2：logistic回归模型中，体力活动相关基因多态性与对应基因多态性之间交互项的P值。 CI：置信区间（Confidence interval）。