Origin and characteristics of human cell line models under investigation.

Abbreviations: PB, peripheral blood; CML, chronic myeloid leukemia; CP, chronic phase; BC, blast crisis; no, number; AML-M2, acute myeloid leukemia M2; DSMZ, German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.1doubling time of subconfluent cells when 3×105 cells were seeded in 100 mm cell culture dishes.2p210BCR-ABL Tet-ON promoter induction with Doxycycline [1 µg/ml].缩略语说明：PB：外周血（peripheral blood）；CML：慢性髓性白血病（chronic myeloid leukemia）；CP：慢性期（chronic phase）；BC：急变期（blast crisis）；no：数量（number）；AML-M2：急性髓系白血病M2（acute myeloid leukemia M2）；DSMZ：德国微生物和细胞培养物收藏中心（German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany）。1. 亚汇合状态细胞的倍增时间：将3×10⁵个细胞接种于100 mm细胞培养皿中时的倍增时间。2. 采用浓度为1 µg/ml的多西环素（Doxycycline）诱导p210BCR-ABL Tet-ON启动子的表达。