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CRC-like organoids with the acquired mutations related to the stage.

NIAID Data Ecosystem2026-03-11 收录

数据链接：

https://figshare.com/articles/dataset/CRC-like_organoids_with_the_acquired_mutations_related_to_the_stage_/9035840 数据链接链接失效反馈

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资源简介：

CRC-like organoids with the acquired mutations related to the stage.

应用场景：

创建时间：

2019-07-24

炎症性肠病基因表达

结肠类器官

With aging, normal human tissues experience expansion of somatic clones that carry cancer mutations. However, whether such clonal expansion exists in the non-neoplastic intestine remains unknown. Here

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Epithelial WNT2B and Desert Hedgehog are necessary for human colonoid regeneration after bacterial cytotoxin injury

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细菌毒素损伤修复

proteomics of human colonoids - comparing control, EspP treated, and EspP-S263A treated

Figshare2020-09-21 更新60

FGF Signaling in the Self-Renewal of Colon Cancer Organoids. FGF Signaling in the Self-Renewal of Colon Cancer Organoids

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FGF信号通路

With their ability to self-renew and simultaneously fuel the bulk tumor mass with highly proliferative tumor cells, cancer stem cells (CSC) are supposedly driving cancer progression. However, the CSC-

NIAID Data Ecosystem50

VDR ChIP-Seq on colonic human organoids

维生素D受体调控

结肠类器官

Genome-wide maps of VDR binding sites in colonic organoids estimulated with calcitriol Overall design: Three independent VDR ChIP-Seq analysis of 3D stem cell enriched cultures of two different patien

NIAID Data Ecosystem70

Prospective derivation of a 'Living Organoid Biobank' of colorectal cancer patients

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药物筛选

In Rspondin-based 3D cultures, Lgr5 stem cells from multiple organs form ever-expanding epithelial organoids that retain their tissue identity. We report the establishment of tumor organoid cultures f

NIAID Data Ecosystem50

CRC-like organoids with the acquired mutations related to the stage.

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