Supplementary Material for: Prevalence of Skin and Skin-Related Diseases in the Rochester Epidemiology Project and a Comparison with Other Published Prevalence Studies

In Olmsted County, Minn., USA, reliable, population-based epidemiologic research studies can be performed because of a unique medical records linkage system, the Rochester Epidemiology Project (REP). Our objective was to summarize the epidemiologic data describing the prevalence of skin and skin-related diseases derived from the REP and to compare the findings with those from other studies worldwide. Retrospectively, we reviewed the results of population-based REP studies reporting the prevalence of skin and skin-related diseases over more than 4 decades and compared them to other published prevalences globally. Prevalences from the REP reported per 100,000 persons were as follows: hidradenitis suppurativa, 130.0; psoriasis, 700.0; psoriatic arthritis in 1992, 100.0, and in 2000, 160.0; Behçet disease, 5.2; scleroderma, 13.8; dermatomyositis, 21.42; systemic lupus erythematosus (SLE), from 30.5 to 122.0 suspected SLE, 32.8; combined SLE, 41.8; discoid lupus erythematosus, 27.6, and cutaneous lupus erythematosus, 70.4 and 73.2 (from 2 studies). Many of the population-based prevalences of specific skin and skin-related diseases derived from the REP are different from those estimated globally. Suggested reasons for disparity in the prevalences globally may include differences in the type of reported prevalence, study methodology, geographic areas, ethnic groups, age distribution, and socioeconomic status.美国明尼苏达州奥姆斯特德县依托一套独特的医疗记录关联系统——罗切斯特流行病学项目（Rochester Epidemiology Project, REP），可开展可靠的基于人群的流行病学研究。本研究旨在汇总源自该项目的皮肤及皮肤相关疾病患病率流行病学数据，并将其与全球其他同类研究结果进行对比。本研究回顾性梳理了四十余年来基于REP开展的、报告皮肤及皮肤相关疾病患病率的人群研究结果，并将其与全球已发表的相关患病率数据进行对比。按每10万人计算的REP报告患病率如下：化脓性汗腺炎130.0；银屑病700.0；1992年的银屑病关节炎患病率为100.0，2000年为160.0；白塞病5.2；硬皮病13.8；皮肌炎21.42；系统性红斑狼疮（systemic lupus erythematosus, SLE）患病率区间为30.5~122.0，疑似SLE为32.8；复合型SLE为41.8；盘状红斑狼疮27.6；皮肤红斑狼疮患病率分别为70.4和73.2（源自两项研究）。本研究纳入的REP人群研究中，多数特定皮肤及皮肤相关疾病的患病率与全球估算值存在差异。造成全球患病率差异的潜在原因可能包括：报告的患病率类型、研究方法、地理区域、人群种族、年龄分布及社会经济地位等方面的不同。