Structural and dynamical studies from the Gothenburg BAG

The Gothenburg BAG was previously a Gothenburg/Lund BAG, but was remodelled in 2021 so as to reflect the realities that the Lund environment was more focused upon addressing their synchrotron radiation needs through MAX IV Laboratory. Moreover, serial crystallography, both at XFELs and using synchrotron radiation, has become a major of interest of several of the scientists at the University of Gothenburg, and this is not covered in the BAG but within another BAG coordinated at the ESRF. Standard MX using cryo-crystallography, as well as standard SAXS studies, are still an important aspect of our work, but now requires less beamtime than the larger BAG used in the past. Moreover, some of this work is connected to methodology developments or used as a stepping stone towards time-resolved crystallography studies. Overall, we have a diverse collection of projects from the groups in Gothenburg which continue to benefit greatly from access to the ESRF.

哥德堡光束线分配组（Gothenburg BAG）前身为哥德堡/隆德光束线分配组，于2021年完成改组，以适配当前的实际研究需求：隆德科研团队更侧重通过马克斯四号实验室（MAX IV Laboratory）满足其同步辐射光源使用需求。此外，串行晶体学（serial crystallography）——包括依托X射线自由电子激光（X-ray Free Electron Laser, XFEL）与同步辐射光源开展的相关研究——已成为哥德堡大学多位科研人员的核心研究方向之一，但此类研究未被本BAG覆盖，而是归属欧洲同步辐射装置（European Synchrotron Radiation Facility, ESRF）协调的另一用户组。当前，依托低温晶体学（cryo-crystallography）的标准大分子晶体学（Macromolecular Crystallography, MX）以及标准小角X射线散射（Small-Angle X-ray Scattering, SAXS）研究仍是本团队工作的重要组成部分，但相较于过往，此类研究所需的光束机时已大幅减少。此外，部分此类工作与方法学开发相关，或作为迈向时间分辨晶体学（time-resolved crystallography）研究的过渡基础。总体而言，哥德堡各研究团队拥有丰富多样的研究项目，这些项目仍将从欧洲同步辐射装置的使用权限中获益良多。