MMIST tutorial imaging and sequencing data

Imaging and sequencing dataset of MCF10A cells responding to ligand treatments, accompanies jupyter-notebook based tutorial using the celltraj software package. Dataset includes live-cell imaging (48 hr duration, 20min intervals), segmentation masks (nuclear and voronoi partitions based upon nuclear centers), single-cell featurization and analysis data, and paired bulk RNA-sequencing data at 24 hours, see: Copperman, Jeremy, Ian C. Mclean, Sean M. Gross, Young Hwan Chang, Daniel M. Zuckerman, and Laura M. Heiser. "Single-cell morphodynamical trajectories enable prediction of gene expression accompanying cell state change." bioRxiv (2024): 2024-01.本数据集为响应配体处理的MCF10A细胞成像与测序数据集，附带基于Jupyter Notebook且使用celltraj软件包的教程。数据集涵盖活细胞成像（时长48小时，采样间隔20分钟）、分割掩码（基于细胞核中心的细胞核分割与沃罗诺伊分区（Voronoi））、单细胞特征化与分析数据，以及24小时时间点的配对批量RNA测序数据，详见： Copperman, Jeremy、Ian C. Mclean、Sean M. Gross、Young Hwan Chang、Daniel M. Zuckerman及Laura M. Heiser。《单细胞形态动力学轨迹可预测细胞状态变化伴随的基因表达》。bioRxiv (2024): 2024-01.