Summary of Laser Treatments for Tattoo Removal

This systematic review includes the following study designs- 7 randomized controlled trials, 2 non-randomized controlled trials, and 27 case series. A total of 33 studies had the quality appraised using specific assessment tools and were given a high, moderate, or low risk of bias. The table provides details for each study, including the associated risk of bias. The primary endpoints of our study were to collect data on laser parameters, treatment methods, patient and tattoo characteristics, clearance rate, and adverse effect rate while providing a qualitative analysis on the results. Our study found that lasers continue to be the gold standard for tattoo removal. Q-switched and picosecond lasers are both effective and safe with black tattoos. However, picosecond lasers demonstrate superiority with blue, green and yellow colors. Lastly, novel techniques (R20 and R0) successfully reduce treatment time while maintaining
good efficacy.

本系统评价（systematic review）纳入以下研究设计类型：7项随机对照试验（randomized controlled trial）、2项非随机对照试验（non-randomized controlled trial）以及27项病例系列研究（case series）。共计33项研究采用专用评估工具完成质量评价，并被评定为高、中、低三级偏倚风险（risk of bias）。本附表详述了各项研究的详细信息，包括其对应的偏倚风险等级。本研究的主要研究终点为：收集激光参数、治疗方案、患者与纹身特征、清除率及不良反应发生率相关数据，并对研究结果开展定性分析。本研究发现，激光疗法仍是纹身去除的金标准。调Q激光（Q-switched laser）与皮秒激光（picosecond laser）在黑色纹身治疗中均兼具有效性与安全性；但皮秒激光在蓝色、绿色与黄色纹身的治疗中展现出更优疗效。最后，新型治疗技术（R20与R0）可在维持良好疗效的前提下，有效缩短治疗时长。