The effects of endothelium removal (E−), L-NAME, losartan, enalapril, SOD, catalase and apocynin on the sensitivity (pD2) and maximal response (Emax) to phenylephrine in aortic rings from cadmium-treated and control rats.

The results are expressed as the mean ± SEM; Emax, maximal effect expressed as a percentage of the response induced by 75 mM KCl; pD2, -log one-half Emax. E- endothelium removal, E+ intact endothelium, SOD, superoxide dismutase. Pvs control rats (#) and cadmium-treated rats (*), determined using Student’s t-test.实验结果以均值±标准误（Standard Error of the Mean，SEM）表示；最大效应值（Emax）：以75 mM氯化钾（KCl）诱导的反应百分比形式呈现；pD2：半数最大效应的负对数。E-代表去除内皮组，E+代表完整内皮组；SOD即超氧化物歧化酶（superoxide dismutase，SOD）。采用t检验（Student’s t-test）分析，以P值比较标记为#的对照组大鼠与标记为*的镉处理组大鼠的组间差异。